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Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. Chemically, mesalamine is 5-amino-2-hydroxybenzoic acid. Chemically, mesalamine is 5-amino-2-hydroxybenzoic acid. Dosage for treating ulcerative colitis The usual dosage for treating ulcerative colitis (UC) is 4,000 mg per day Pentasa 500 mg Sachet is an anti-inflammatory medicine used for the treatment of ulcerative colitis, a condition characterized by swelling and scarring of the colon and rectum. Dosage for treating ulcerative colitis The usual dosage for treating ulcerative colitis (UC) is 4,000 mg per day Pentasa 500 mg Sachet is an anti-inflammatory medicine used for the treatment of ulcerative colitis, a condition characterized by swelling and scarring of the colon and rectum. 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